Effects of rivaroxaban on routine coagulation screening tests using commonly used reagents
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چکیده
منابع مشابه
What is the effect of rivaroxaban on routine coagulation tests?
A 78-year-old female presents to the emergency department with a traumatic hip fracture. Her past medical history is significant for atrial fibrillation for which she receives rivaroxaban 20 mg daily. Her dose was last taken 12 hours ago. Routine bloodwork conducted in the emergency department shows prothrombin time, international normalized ratio, and activated partial thromboplastin time with...
متن کاملEffects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assays.
INTRODUCTION Rivaroxaban is an oral direct factor Xa inhibitor developed for prophylaxis and treatment of thromboembolic disorders. Laboratory monitoring is not necessary but the dose-dependent effects on common reagents and assay procedures are largely unknown. OBJECTIVES To investigate the effect of rivaroxaban on commonly used coagulation assays. MATERIALS AND METHODS Rivaroxaban was add...
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Routine coagulation tests have been used for many years in the preoperative setting in the belief that they identify patients who may have acquired or congenital bleeding disorders, and on the assumption that testing will predict perioperative bleeding allowing treatment to be given and prevent it. Coagulation ‘screens’ typically include the prothrombin time (PT) and the activated partial throm...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2016
ISSN: 0007-1048
DOI: 10.1111/bjh.14230